There are many different SARMs on the market, all with various traits and outcomes. While they all have similar
effects, there is absolutely differentiation and it’s wise to pick the best SARM for you. Below is a rundown of the most common and popular SARMs on the market.

• Ostarine (Enobosarm, MK-2866, GTx-024, S-22)

Without a doubt the most popular SARM around, Ostarine is well-researched and seemingly has the best effects. With clinical trials in humans being completed and underway, it has a very good safety profile and effects to go along with it.

Usually, people experience around 5-10lbs of muscle mass gain from a single cycle of Ostarine even with average doses. A usual Ostarine cycle is around 6-8 weeks long as with all SARMs and mild testosterone suppression is
noticed at moderate-high doses.

It’s unlikely a PCT regimen is required after using Ostarine however it’s not uncommon, especially if combined with other SARMs, anabolics, or used in high quantities. Seemingly, Ostarine is the best SARM for beginners and very easy to use. Dosing is usually once a day every day for the entire cycle.

Ostarine is deemed safe to be used by women and elderly folk and has a minor impact on other sex characteristic and hormones.

• Ligandrol (LGD-4033)

Often used in the bodybuilding and fitness world, Ligandrol is a common yet slightly less used SARM compared to others. Developed to combat muscle wasting diseases and osteoporosis, the effects of Ligandrol are certainly
noticeable.

Ligandrol is relatively powerful and solid amounts of muscle mass are shown to be gained from a typical 6-8 week cycles. Improved bone density, injury recovery, and performance can be noticed across the board. LGD-4033 is
rather well researched and most side-effects can be attributed to testosterone suppression – reduced libido,
lethargy, changes in appetite and more.

Many people have noticed significant amounts of testosterone suppressions when using LGD-4033 at moderate-high doses, and so it’s highly recommended to get your blood levels checked before, during, and after an LGD-4033 cycle. A PCT regimen may be required to have the best experience with Ligandrol.

• Testolone (RAD-140)

Another very common SARM, Testolone/RAD-140 is being developed by Radius Health Inc. and being researched for its impact on helping muscular dystrophy and breast cancer. Testolone aims to act as an alternative to testosterone, of course attempting to avoid the side-effects and unwanted secondary sex characteristics.

Many benefits from testosterone therapy can be had from RAD-140 such as improved anabolic growth, bone density increase, libido increase, and improvements to sleep and energy levels among other traits.

Though RAD-140 is still being researched and tried, its analogous chemistry to testosterone leads us to believe that the long term health consequences are benign and a non-issue. RAD-140 is usually dosed once a day for an entire 6-8 week cycle.

As a result, Testolone is also thought to be safe to be used by women and elderly patients, however it may induce
testosterone suppression in men. It’s recommended to get a blood panel done before, during, and after a cycle since RAD-140 is believed to suppress natural testosterone production more than other SARMs.

A post-cycle testosterone therapy solution may be required after a cycle of Testolone, however blood panel results will be the only real revealing method. Ensure you monitor hormone levels to get the best results from RAD-140,
especially at high doses.

• Andarine (S-4)

Second to its brother, Ostarine, Andarine was under development by the same GTx Inc. until being abandoned in favor of the other. While Andarine certainly possesses some excellent traits with muscle growth and other factors, some noticeable side-effects draws people away.

Usually affecting the vision, high doses of Andarine are known to produce a slight yellow tint to the vision, which while thought to not be detrimental long term, can be discomforting to most people.

Andarine has similar testosterone suppression attributes as Ostarine does and doesn’t often need a PCT regimen unless in high doses. Andarine like Ostarine is thought to be safe to be used by elderly patients and women and has few effects on hormones and secondary sex
characteristics.

• YK-11

A lesser-known yet plenty powerful substance, YK-11 is particularly interesting as it allows the body to develop or gain muscular capacity quicker than normal. By signaling the release of follistatin – the protein responsible for
growth of muscle tissue, strength and mass increases are directly benefitted in a more organic matter.

YK-11 is a derivative of DHT and thusly considered an anabolic SARM. However, it does not trigger or release
hormones in any way and influence those systems. It’s unlikely for much if any mass to be gained if the user is not working out.

As a result, a cycle of YK-11 avoids much of the associated side-effects of anabolic steroids, hormones, and even other SARMs. While it’s hard to find and the research is still underway, YK-11 is a particularly interesting compound.

There are many other substances which fall under the umbrella of SARMs but aren’t technically considered as such. These are:

• Cardarine (GW-501516)

Cardarine, also known as GW-501516, is known to be a powerful performance enhancing substance, especially
regarding cardiovascular exercise. While its benefits are absolutely there are quite strong, the ambiguous safety
profile leads many users away.

Cardarine was abandoned in development after the subjects being tested on developed tumorous growths after being exposed to extremely high levels of the drug among others.

While no one can say for sure if Cardarine can give you cancer or not and if the studied tests are a valid indicator of its downsides, research nonetheless was abandoned and using Cardarine is at your own risk. The benefits are very
powerful but not worth the risk to some.

• Ibutamoren (MK-677)

Not considered a SARM either but used in conjunction alongside many, Ibutamoren is a non-peptide agonist of the hunger hormone Ghrelin, and a growth hormone secretagogue. This is an excellent agent if you want to help spur growth in a natural way.

Ibutamoren is being researched under the name Oratrope and was given the green light by being granted
Investigational New Drug Status. It has a rather good health and safety profile and has little in the way of side-effects.

MK-677 initiates the secretion of multiple beneficial hormones such as growth hormone, IGF-1 (insulin-like growth factor), Ghrelin, and more without affecting cortisol levels. Ibutamoren does not have any known effect on androgen receptors.

A lot of reports note an improved quality of sleep, a much increased appetite, stronger gains of lean muscle mass, and a general increase in strength. As it doesn’t affect testosterone levels or any other sex hormone, a PCT is not required and overall Ibutamoren is fine for elderly people and women to use.

Oftentimes MK-677 is stacked with other SARMs to work in conjunction and provide great benefit. Definitely a compound to keep in the back of your mind.

• Stenabolic (SR-9009)

Also not a SARM, Stenabolic, or SR-9009 is what’s known as a Rev-ErbA agonist. In essence, Stenabolic has been shown to provide a significant increase in exercise capacity. Due to its short 4 hour half-life, Stenabolic is often used in a way similar to a pre-workout.

SR-9009 is thought to have fat-burning abilities by helping to empty glycogen reserves in the body. This triggers
hyperglycemia, increasing available energy sources while guiding the body to use fat cells as a fuel source.

There is still not too much information out there on Stenabolic, its exact biomechanics, and efficacy, however some swear by its ability to boost workouts dramatically without much in the way of side-effects.

Of course you can expect a lean muscle mass increase. While this widely depends on dose, diet, exercise routine and other factors, people often notice between 5-15lbs of muscle mass increase throughout a usual cycle of a select SARM.

Here are some other benefits and things you can expect from SARMs.

• Lean muscle mass increase

Almost all clinical trials have noted a significant increase in lean muscle mass, even from very low doses. Higher doses did result in more gains, however low-moderate quantities still showed very good results.

• Bone density increase

This is particularly useful for combatting Osteoperosis and a key research point for many of the clinical applications, bone density is likely to improve with SARMs.

• Increased libido

It’s not uncommon to notice a higher libido. Sex drive will likely increase, albeit not to the same intensity as traditional anabolic agents or hormones like testosterone.

• Improved sleep patterns

Many people notice improved REM sleep and have an easier time falling asleep. This is generally associated with a variety of SARMs however not guaranteed or particularly well studied.

• Fat loss/recomposition

As the body begins to prioritize fat cells as a source of fuel rather than carbohydrates, fat is essentially ‘burned’ off. This is particularly useful after bulking and trying to recompose the body from fatty to muscular.

• Prevents catabolism

Another aspect linked to the above fat loss, SARMs help the body preserve muscle mass while at a caloric deficit. This helps keep existing muscle mass intact and helps greatly during a cut.

• Higher muscular endurance

Cardio-related activities have been noted to improve as mitochondrial activity shifts and improve energy delivery to muscle cells. This is not particularly well-documented however suggested to be true.

• Improved strength

With lean muscle mass increases comes higher potential strength output. Combined with improved cardiovascular ability

• Higher vascularity

As fat quantities decrease, vascularity improves significantly. Arterial and venial channels are thought to grow to supply the body and muscles with more blood.

• Soft tissue reparation

While not particularly documented, recovery for damaged ligaments, tendons, and other soft tissue is thought to
improve as cellular genesis improves systemically regarding soft and hard tissue.

• Injury recovery

As a result, any injury involving bone, ligament, tendon, and muscle is seemingly improved. SARMs are particularly useful when combined with other agents used for injury recovery such as BPC-157 or testosterone

Nothing is perfect and without repercussions. Thankfully, SARMs as a whole are generally safe to use and have a nice safety profile. With that in mind, the research is still limited and there may very well be things that we don’t know yet.

Some common cons/side-effects from SARMs as a whole are as follows:

• Potential testosterone suppression

While SARMs avoid much of the testosterone suppression associated with many anabolic agents, moderate to high doses will likely cause partial or full testosterone suppression.

We recommend getting your bloods checked before, during, and after a cycle to carefully monitor your hormone levels. A post-cycle therapy (PCT) is occasionally advised, especially to those using higher doses.

• Sleep problems

While sleep cycles may also improve, some have reported worsened sleep patterns, usually due to high levels of energy and other factors. Consider a ZMA (Zinc Magnesium Aspartate) supplement to help with sleep.

• Increased appetite

Certain SARMs trigger the stimulus of the hunger hormone ghrelin. As a result, some people develop an undesirably powerful appetite. This may influence your mood and sleep patterns.

• Mood swings and instability

While hunger is a factor, a relatively rapid shift in hormone levels and internal biological function may destabilize a person’s mood frequently. Though not nearly as severe as traditional anabolic steroids, some people may become easily aggravated, aroused, and aggressive.

• High energy levels

Restlessness may increase, especially while sitting down for long periods of time (ie; at work, in a classroom setting, etc). This may play into worsened quality of sleep.

• Hormonal imbalances

Hormonal imbalances carry a variety of side-effects regarding acne, sexual (dis)function, mood, sleep patterns, and more. We recommend getting a pre, during, and post-cycle blood panel and evaluating your hormone levels.

• Allergic reaction

A rare yet possible side-effect, allergic reactions can be considered a severe side-effects and it’s highly recommended to cease use immediately. Allergic reactions are a tell-tale sign that something is wrong and the body treats the
foreign compound as a threat rather than a benefactor.

In the case that you believe you’re having an allergic reaction from SARMs (hives, difficulty breathing, itchiness,
excessive sweating, etc), stop immediately. While cases are few and far between regarding allergic reactions from SARMs, it is absolutely possible and may have critical consequences.

Please play it safe and if you develop any strange symptoms, absolutely stop and go consult a licensed physician.

While no deaths have been attributed to SARMs, there have been cases of hospitalizations, seizures, and others from severe allergic reactions. Start low with your dose and if anything strange happens, calmly evaluate your situation.

Peptides have gained traction and for good reason – they have a great safety profile, a nice array of benefits, and are cost effective in general. On the other hand, they almost all require injections (usually subcutaneous), which is enough to scare away many people.

SARMs don’t require injections and are almost always available to be taken in pill form.

Peptides don’t have much of their mechanics related to the androgen system and rather function exactly as the amino acid they’re designed to be/emulate. Peptides also often offer localized benefit while SARMs are systematic.

Peptides are excellent to look into as well, especially for injury recovery. Growth hormone secretagogues and other hormone influencing factors generally fall into the peptide category.

For example; BPC-157, IGF-1, and CJC-1295 are all peptides and not SARMs.

Steroids have been widely used in bodybuilding, athletics, and for general therapeutic purposes for many decades.
As a result, steroids are very well studied and generally well understood, with a very comprehensive safety profile and understanding of the side-effects.

With that in mind, almost all steroids have powerful side-effects compared to SARMs, many of which highly
undesirable.

Yes, steroids will absolutely be more effective for raw anabolic growth; however the sides are far too much for some. Of course, many steroids are only available in injectable form, though some do come in pill form as well.

Think of steroids like a shotgun and SARMs to be like a carefully placed round from a small rifle. You’re going to hit the target and more with usual anabolic steroids, however you might hit some things you don’t want like balding and gynecomastia, while SARMs will get the job done with more precision but not with as much power.

In our eyes, it’s nice to avoid super powerful substances since this is our own biology we’re playing with, and we prefer precision and low side-effects over raw power and overhaul.

Obvious answer: It depends. While anyone can use SARMs at any time and see measurable results, we often
recommend people to be in fine athletic shape before starting. Try and reach the limits of your natural growth and strength. If you’re already on a proper workout plan, diet, and have dialed in your training/lifestyle properly, then SARMs can be the perfect thing for you to break through.

On the other hand, people coming from a significant disadvantage in terms of physicality can also benefit greatly. It’s imperative to do proper research though and even more important to follow a proper diet and training program if you do being. Following those steps, you can achieve excellent results quickly.

Treat these compounds seriously as they’re capable of helping tremendously, and it’d be wise to dial in a proper
regimen weeks prior to beginning SARMs.

This all depends on the SARMs you take, however most fall under the same usage guidelines; once a day, every day, at the same time of day, for however long the cycle is. Most people typically run a cycle for between 6-8 weeks, though there are outliers.

Occasionally people run a cycle for 4 weeks, however this is often lackluster as it takes ~2-3 weeks to even begin
seeing/feeling any change from SARMs.

On the other hand, some people run a cycle for up to 12 weeks which in our mind is a bit excessive. It’s vital to let the body recover and go back to baseline, and negative-side effects will only increase the longer you use SARMs for.

Take them on an empty stomach, preferably between breakfast and lunch, consistently for the entire cycle. Though it’s not absolutely vital to be so consistent, your body will likely acclimatize to the new compound(s) easier when scheduled.

SARMs are often in pill or liquid form. They’re stable compounds and while they should be stored in a dark, cool place, they can last a while in storage.