Legacy Laboratories Nolvadex
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Legacy Laboratories Nolvadex
Legacy Laboratories Nolvadex is an anti-estrogen drug used in the treatment of breast cancer that has metastasized, i.e. spread to other parts of the body. In certain patients, it is also used to treat breast cancer post-surgery and after radiation therapy. Moreover, Nolvadex may also be administered to high-risk individuals to minimize their chances of developing breast cancer.
However, apart from these conventional uses, Nolvadex might have benefits for bodybuilders, since it significantly increases the amount of testosterone produced by the body. Bodybuilders also use the drug to preserve their muscle gains and prevent any problems with gynecomastia (imbalance of estrogen and testosterone).
But despite these benefits, it is important to understand that the estrogen antagonist might also have adverse effects and should be used with care.
This article will help you understand what Nolvadex is, how it works within the body, and what gym-goers need to watch out for if they plan to use buy nolvadex.
What is Nolvadex?
Nolvadex (tamoxifen citrate) is an anti-estrogen also referred to as pro-drug. This type of steroid acts as an antagonist of the estrogen receptor in the brain and the breast regions, completely preventing the normal influence and effects of the hormone on tumors in those areas. In the brain, tamoxifen prevents the conversion of testosterone to estrogen, which in turn keeps estrogen levels low.
In 2012, researchers found that tamoxifen was frequently added to supplements used by bodybuilders, without being mentioned on the label.
How Does it Work?
Legacy Laboratories Nolvadex is a hormone therapy–based drug. Hormone therapy has been used to treat cancer based on the fact that receptors for particular hormones that influence cell growth are located on the surface of certain tumor cells.
Hormone therapy can work by either inhibiting the production of a certain hormone, blocking their specific receptors or by substituting analogs in place of the active hormone which cannot be used by the tumor cell.
Nolvadex works by blocking estrogen receptors on the hypothalamus. This causes the brain to sense that the body is deficient in the hormone, resulting in a surge of gonadotropins and increasing the synthesis of sex hormones, most notably testosterone.
Benefits
Nolvadex is considered beneficial in the fitness arena because it can efficiently block estrogen production, which in turn allows the body to create testosterone in larger amounts and help form muscle.
Individuals that take anabolic steroids (synthetic versions of testosterone) often have to deal with certain unpleasant and serious side effects. Bodybuilders and fitness enthusiasts who begin to experience these effects can use tamoxifen citrate to reverse or block some of them.
One such example is when men consume testosterone in very large doses, it is converted into estrogen. This can cause the development of gynecomastia, a condition in which males can grow breasts and even start producing milk. Tamoxifen prevents this by blocking the body from producing estrogen.
Researchers from the University of Glamorgan reported a 22 percent increase in the number of gym-goers using tamoxifen, particularly male bodybuilders, to neutralize the adverse side effects of steroids.
How Long Does It Take to Start Working?
In hormone therapy, Legacy Laboratories Nolvadex is typically prescribed at 40mg per day for the first two weeks, followed by 20mg per day for the last 2 weeks.
Bodybuilders usually consume the drug in larger doses as opposed to the recommended dosage, and since their purpose is to develop muscle and avoid estrogen build-up, the effects and their occurrence vary according to each individual.
How Long Do the Effects of Nolvadex Last?
*can’t find a specific answer*
How Long Does It Take Nolvadex to Leave the System?
It takes at least two months for Nolvadex to clear from the system.
Side Effects
Even though low estrogen levels are usually considered gainful by bodybuilders, estrogen is important for the buildup of muscle mass and boost libido as well. Bodybuilders using artificial testosterone enhancing compounds along with tamoxifen often miss out on these two valuable aspects which normally accompany testosterone elevation.
Apart from this, common side-effects of using tamoxifen include:
- Hot flashes
- Leg and muscle cramps
- Nausea
- Thinning hair
- Headache
Serious side effects include:
- Blurred vision
- Eye ache
- Mood alterations
- Swelling in ankles/feet
- Vomiting
- Abdominal discomfort
- Skin discoloration
- Darkening of urine
- Difficulty breathing
- Itchiness/rash
Precautions
Individuals dealing with the following conditions should not take this medication:
- Blood clots
- Diabetes
- High blood pressure
- High cholesterol
- Liver disease
- Cataracts
- Liver disease
Bottom Line
The use of prescription drugs for building muscle mass and increasing testosterone levels is on the rise. However, these drugs are designed for specific medicinal purposes and effects and must be used with caution.
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Frequently Asked Questions (FAQs)
How Should I Take Nolvadex?
Take nolvadex regularly and at the same time each day for the most benefit. As a hormone therapy, it is generally prescribed at 40mg every day for the first 2 weeks, and reduced to 20mg per day for the last 2 weeks of treatment.
How Should I Use Nolvadex for Best Results?
Tamoxifen tablets should be swallowed whole. The medicine should be taken at the same time every day with a glass of water. If a dose is missed, do not double the dose the next day.
How Should I Take Liquid Nolvadex (Oral Solution)?
Follow the instructions on the prescription label very carefully. Generally, 20 mg of tamoxifen is given as 10 mL, which is the equivalent of two teaspoons. Use an appropriate measuring device to accurately measure the dosage.
When Should You Take Nolvadex?
Dosages greater than 20 mg are generally divided in half and taken twice daily, i.e. morning and evening, or as directed by the physician. For oral solution, carefully measure the dose using an appropriate measuring device/spoon (a household spoon will not measure the correct dose).
How Much Nolvadex Should You Take?
For hormone therapy, the dosage will depend on your medical condition and response to treatment. To build muscle, always consult an expert in the field before using any medication.
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References
- Elsharkawy A. M., McPherson S., Masson S., et al., Cholestasis Secondary to Anabolic Steroid Use in Young Men. BMJ (2012); 344 : e468. Available at DOI:10.1136/BMJ.e468
- Batty, David. Gymgoers ‘are abusing tamoxifen’. The Guardian (2006); Available at https://www.theguardian.com/society/2006/jun/15/health.lifeandhealth1
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